Serena Williams's Grand Slam Titles, Finals, Records
Serena Williams's record in Grand Slam major singles finals.
| YEAR | EVENT | WINNER | RUNNER-UP | SCORE |
| 2019 | US Open | Bianca Andreescu | Serena Williams | 6-3, 7-5 |
| 2019 | Wimbledon | Simona Halep | Serena Williams | 6-2, 6-2 |
| 2018 | US Open | Naomi Osaka | Serena Williams | 6-2, 6-4 |
| 2018 | Wimbledon | Angelique Kerber | Serena Williams | 6-3, 6-3 |
| 2017 | Australian Open | Serena Williams | Venus Williams | 6-4, 6-4 |
| 2016 | Wimbledon | Serena Williams | Angelique Kerber | 7-5, 6-3 |
| 2016 | French Open | Garbine Muguruza | Serena Williams | 7-5, 6-4 |
| 2016 | Australian Open | Angelique Kerber | Serena Williams | 6-4, 3-6, 6-4 |
| 2015 | Wimbledon | Serena Williams | Garbine Muguruza | 6-4, 6-4 |
| 2015 | French Open | Serena Williams | Lucie Safarova | 6-3, 6-7(2), 6-2 |
| 2015 | Australian Open | Serena Williams | Maria Sharapova | 6-3, 7-6(5) |
| 2014 | US Open | Serena Williams | Caroline Wozniacki | 6-3, 6-3 |
| 2013 | US Open | Serena Williams | Victoria Azarenka | 7-6, 6-7, 6-1 |
| 2013 | French Open | Serena Williams | Maria Sharapova | 6-4, 6-4 |
| 2012 | US Open | Serena Williams | Victoria Azarenka | 6-2, 2-6, 7-5 |
| 2012 | Wimbledon | Serena Williams | Agnieszka Radwanska | 6-1, 5-7, 6-2 |
| 2011 | US Open | Samantha Stosur | Serena Williams | 6-2, 6-3 |
| 2010 | Wimbledon | Serena Williams | Vera Zvonareva | 6-3, 6-2 |
| 2010 | Australian Open | Serena Williams | Justine Henin | 6-4, 3-6, 6-2 |
| 2009 | Wimbledon | Serena Williams | Venus Williams | 7-6(3), 6-2 |
| 2009 | Australian Open | Serena Williams | Dinara Safina | 6-0, 6-3 |
| 2008 | US Open | Serena Williams | Jelena Jankovic | 6-4, 7-5 |
| 2008 | Wimbledon | Venus Williams | Serena Williams | 7-5, 6-4 |
| 2007 | Australian Open | Serena Williams | Maria Sharapova | 6-1, 6-2 |
| 2005 | Australian Open | Serena Williams | Lindsay Davenport | 2-6, 6-3, 6-0 |
| 2004 | Wimbledon | Maria Sharapova | Serena Williams | 6-1, 6-4 |
| 2003 | Wimbledon | Serena Williams | Venus Williams | 4-6, 6-4, 6-2 |
| 2003 | Australian Open | Serena Williams | Venus Williams | 7-6(4), 3-6, 6-4 |
| 2002 | US Open | Serena Williams | Venus Williams | 6-4, 6-3 |
| 2002 | Wimbledon | Serena Williams | Venus Williams | 7-6(4), 6-3 |
| 2002 | French Open | Serena Williams | Venus Williams | 7-5, 6-3 |
| 2001 | US Open | Venus Williams | Serena Williams | 6-2, 6-4 |
| 1999 | US Open | Serena Williams | Martina Hingis | 6-3, 7-6 |
- Grand Slam Finals Appearances: 33
- Grand Slam Titles: 23
- Grand Slam Finals Record: 23-10