on Friday in five sets to move into the fourth-round in Melbourne.
Kohlschreiber, the No. 29 seed, looked fitter than Roddick in a 6-4, 3-6, 7-6(9), 6-7(3), 8-6 victory that lasted almost four hours.
Roddick let loose on chair umpire Emmanuel Joseph and "talked smack" to Kohlschreiber during the match, but that didn't aid the American who at the same time served a career-high 42 aces.
Roddick fought off four match points on his serve before succumbing.
"I took his best stuff for five sets and I thought I was going to get him to break or to fold," Roddick said. "I thought if I kept it on him long enough that that would happen. Tonight he played like a great, great player. His backhand was extremely impressive."
Roddick was the lone upset victim Friday in Melbourne as seeds (2)
Rafael Nadal (d. (28)
Gilles Simon), (4)
Nikolay Davydenko (d.
Marc Gicquel), (8)
Richard Gasquet (d. (31)
Igor Andreev in four), (14)
Mikhail Youzhny (d. (20)
Ivo Karlovic), (23)
Paul-Henri Mathieu (d.
Stefan Koubek 8-6 in the fifth), and (24)
Jarkko Nieminen (d. Fish in four) all advanced into the fourth round.
Also a winner was surging Frenchman
Jo-Wilfried Tsonga, who topped Spaniard
Guillermo Garcia-Lopez in straight sets.
Up Saturday in Melbourne are (7) Fernando "Gonzo" Gonzalez vs. Croat riser
Marin Cilic, (1)
Roger Federer vs. Serb
Janko Tipsarevic, (19)
Lleyton Hewitt vs. (15)
Marcos Baghdatis, (12)
James Blake vs.
Sebastien Grosjean, (3)
Novak Djokovic vs.
Sam Querrey, (21)
Juan Monaco vs. (13)
Tomas Berdych, (10)
David Nalbandian vs. (22)
Juan Carlos Ferrero, and rappin'
Vincent Spadea vs. (5)
David Ferrer.